Multivitamin use and telomere length in women

doi:10.3945/ajcn.2008.26986

TABLE 2

Average telomere length according to frequency of multivitamin use in subgroups^¹

		Users
	Nonusers	<3 d/wk	4–6 d/wk	Daily	P for trend^²	P for interaction^³
Age						0.6
<53 y
No. of subjects	122	27	35	99
Lsmean ± SE	5586 ± 141	5429 ± 233	5893 ± 213	5824 ± 146	0.05
≥53 y
No. of subjects	81	22	15	180
Lsmean ± SE	5168 ± 138	5291 ± 237	5373 ± 286	5494 ± 126	0.02
BMI						0.5
<30 kg/m²
No. of subjects	137	34	37	190
Lsmean ± SE	5434 ± 126	5483 ± 194	5705 ± 197	5624 ± 122	0.08
≥30 kg/m²
No. of subjects	66	15	13	89
Lsmean ± SE	5230 ± 162	5009 ± 314	5618 ± 336	5708 ± 158	0.008
Smoking						0.6
Never
No. of subjects	87	24	26	139
Lsmean ± SE	5483 ± 139	5307 ± 234	5717 ± 233	5628 ± 123	0.2
Ever
No. of subjects	116	25	24	140
Lsmean ± SE	5368 ± 131	5450 ± 230	5765 ± 230	5788 ± 135	0.002
Diabetes or cardiovascular disease				0.4
No
No. of subjects	166	39	47	218
Lsmean ± SE	5587 ± 104	5508 ± 180	5817 ± 168	5796 ± 103	0.03
Yes
No. of subjects	37	10	3	61
Lsmean ± SE	4908 ± 219	4966 ± 390	5813 ± 667	5590 ± 187	0.004

¹Least-squares mean (Lsmean) ± SE values were derived from generalized linear regression models, adjusted for age, race, BMI, education level, cigarette smoking, presence of diabetes or cardiovascular diseases, energy intake, perceived stress level, self-reported health status, and physical activity. Stratified variables were also adjusted for in the subgroup analysis when possible.

²Tested by including the median of each category as a continuous variable in the regression model.

³Tested by including a multiplicative term in the regression model.