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Table 2

Summary of included case series

ReferencesPeer reviewed?SampleType of OMManipulative treatmentResultsAdverse eventsQuality?
Degenhardt and Kuchera28Yes5 Males, 3 Females; 7-35 moRecurrent OMOsteopathic manipulative treatments5 had no recurrence; 1 bulging tympanic membrane; 1 had 4 additional OM recurrences; 1 underwent surgery.Not statedGood
Zhang and Snyder29Yes12 Males, 9 Females;
9 mo-9 y
AOMChiropractic:
toftness adjustments
Red, bulging tympanic membrane was found in all cases. 95% of the patients' tympanic membrane returned to normal after 1 adjustment.Not statedFair
Fallon30Yes315 patients; 6 mo-5 y127 AOM; 104 serous/chronic OM; 10 mixed OMChiropractic adjustments% recurrence per diagnosis: 11% with acute; 16% with chronic; 30% with mixed; 18% with no diagnosis.Not statedGood
Fysh31Yes3 Males, 2 Females;
13 mo-5 y
Chronic recurrent OMChiropractic adjustmentsEach patient responded favorably to treatment by day 3 to week 8.“No complications noted”Excellent
Froehle32Yes46 patients; ≤ 5 yEar discomfort/infectionChiropractic: sacral occipital technique & modified applied kinesiology93% of all episodes improved, with 75% improving within 10 d or less.Not statedGood
< AOM, Acute otitis media; mo, month(s); OM, otitis media; y, year(s).