Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
PMC full text:
Spine J. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as:
Spine J. 2014 Jul 1; 14(7): 1106–1116.
Published online 2013 Oct 16. doi:  10.1016/j.spinee.2013.07.468

Table 3

Responders (≥ 50% Individual Improvement)

Observed unadjusted % of responders
Slope (95% CI) Adjusted difference in percentage of responders (95% CI)
SMT 0SMT 6SMT 12SMT 18per 6 SMT sessionsSMT 0 vs SMT 6SMT 0 vs SMT 12SMT 0 vs SMT 18
Pain intensity
    6 wk32.628.346.445.05.5 (1.3, 9.8)*−3.7 (−16.2, 8.8)13.7 (0.6, 26.9)13.0 (−0.4, 26.5)
    12 wk28.438.449.537.03.8 (−0.5, 8.1)10.0 (−3.2, 23.1)21.1 (7.7, 34.6)*8.9 (−4.2, 21.9)
    18 wk32.637.443.347.04.8 (0.5, 9.2)4.3 (−9.1, 17.6)10.3 (−3.3, 23.9)14.2 (0.5, 27.9)
    24 wk36.840.440.242.01.4 (−2.9, 5.7)3.7 (−10.0, 17.4)3.2 (−10.5, 16.9)4.9 (−8.7, 18.4)
    39 wk32.641.445.447.04.8 (0.5, 9.1)9.0 (−4.5, 22.5)13.0 (−0.7, 26.6)14.6 (1.1, 28.1)
    52 wk37.947.541.248.02.5 (−1.9, 6.9)10.2 (−3.5, 23.9)3.9 (−9.8, 17.6)10.6 (−3.2, 24.4)
Functional disability
    6 wk49.547.550.542.0−0.1 (−0.5, 0.3)−2.0 (−16.1, 12.0)0.9 (−13.2, 15.1)−7.5 (−21.4, 6.5)
    12 wk43.249.559.855.04.4 (0.0, 8.8)6.2 (−7.7, 20.0)16.8 (2.9, 30.6)*11.5 (−2.4, 25.4)
    18 wk50.554.563.956.02.5 (−1.9, 6.9)3.7 (−10.4, 17.9)13.5 (−0.3, 27.2)3.5 (−8.8, 19.3)
    24 wk49.551.559.854.02.2 (−2.2, 6.6)2.5 (−11.5, 16.5)10.4 (−3.4, 24.3)4.8 (−9.1, 18.6)
    39 wk51.656.661.954.01.2 (−3.2, 5.6)4.9 (−9.0, 18.8)10.4 (−3.4, 24.2)2.5 (−11.5, 16.4)
    52 wk58.957.657.762.00.8 (−3.5, 5.2)−1.1 (−14.8, 12.6)−1.4 (−15.4, 12.6)2.7 (−11.0, 16.5)

SMT, spinal manipulative therapy group.

Unadjusted group percentages are from original data without imputation; slopes and group differences in responders are computed from imputed data adjusted for the baseline covariates. Positive signs of slopes and mean differences were computed to favor higher doses of SMT.

*P < .025
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