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Fig 1.

Brighton criteria for the diagnosis of BJHS.

Major Criteria
• Beighton score of ≥ 4 (Fig. 2)
• Arthralgia for longer than 3 months in 4 or more joints
Minor Criteria
• Beighton score of 1, 2, or 3 (Fig. 2)
• Arthralgia (> 3-month duration) in 1-3 joints or back pain (> 3-month duration) or spondylosis, spndylolysis/spondylolisthesis.
• Dislocation or subluxation in more than one joint, or in one joint on more than one occasion.
• Three or more soft tissue lesions (eg, epicondylitis, tenosynovitis, bursitis)
• Marfanoid habitus (tall, slim, span greater than height [> 1.03 ratio], upper segment less than lower segment (< 0.89 ratio), arachnodactyly)
• Skin striae, hyperextensibility, thin skin, or abnormal scarring
• Ocular signs: drooping eyelids, myopia, antimongoloid slant
 • Varicose veins, hernia, or uterine or rectal prolapse, mitral valve prolapse
Requirement for diagnosis
BJHS is diagnosed in the presence of 2 major criteria, one major criterion plus 2 minor criteria, or 4 minor criteria. Two minor criteria will suffice where there is an unequivocally affected first-degree relative in family history. The syndrome is excluded by the presence of Marfan or Ehlers-Danlos syndrome (other than the hypermobility type of Ehlers-Danlos syndrome, formerly EDS III).