This study evaluated polyunsaturated fatty acids in erythrocytes
from 22 preeclamptic women and 40 normotensive women. After
adjusting for variables women with the lowest levels of omega-3
fatty acids were 7.6 times more likely to have their pregnancies
complicated by preeclampsia as compared with those in women with
the highest levels of omega-3 fatty acids. A 15% increase in the
ratio of omega-3 to omega-6 fatty acids was associated with a 46%
reduction in the risk of preeclampsia. Low erythrocyte levels of
omega-3 fatty acids and high levels of omega-6 fatty acids and in
particular arachidonic acid are associated with an increased risk
of preeclampsia. 22330 [obs]
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