Proc Natl Acad Sci USA 1997 (Oct 14); 94 (21): 11149–11151 ~ FULL TEXT
Nestle M
Department of Nutrition and Food Studies, New York University, 35 West 4th Street, 10th Floor, New York, NY 10012-1172, USA. nestlem@is2.nyu.edu
Epidemiologic and animal studies have associated certain food plants with pronounced reductions in cancer risk. Among such plants are cruciferous (mustard family) vegetables of the genus Brassica: broccoli, cabbage, cauliflower, and Brussels sprouts, among others. National committees have recommended consumption of these vegetables for cancer prevention since the early 1980s 12. What characteristics of these vegetables might protect against carcinogenesis? Fahey et al. 13 directly address this important question. Brassica vegetables contain little fat, are low in energy, and are sources of vitamins, minerals, and fiberall aspects linked to cancer protection. They also contain a large number of phytochemicals, some of which protect against carcinogenesis in various in vitro and animal testing systems 11. Table 2 summarizes the principal attributes and components of cruciferous vegetables that singly or together might protect against carcinogenesis.