Therapiewoche 1980; 30: 5922–5928
The influence of glucosamine sulfate (Dona® 200-S) or phenylbutazone on arthrotic changes of the spinal column was tested in 80 patients. The use of several objectifiable parameters (Schober test, Lasegue test, distance from finger tips to floor when bending over) showed that combined oral and intramuscular administration of glucosamine sulfate for vertebral syndromes was as effective as a standard therapy with phenylbutazone. However, the average time of treatment required to achieve a clinically relevant result was signifcantly shorter. No side effects were observed.
Oral administration of Dona 200-S coated tablets is recommended for mild to medium arthroses, older patients, patients with fear of intraarticular injections, continuity of medication on non-injection days, treatment of joints that are difficult to access, and long-term and repeated therapy.