Boswellia serrata This section was compiled by Frank M. Painter, D.C.
Send all comments or additions to: Frankp@chiro.orgIf there are terms in these articles you don't understand, you can get a definition from the Merriam Webster Medical Dictionary. If you want information about a specific disease, you can access the Merck Manual. You can also search Pub Med for more abstracts on this topic.
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Boswellia Articles
Boswellia's Effectiveness in the Treatment of Osteoarthritis
NHI-On-Demand ~ 8-04-2008
A recent study published in the journal Arthritis Research & Therapy found that patients taking an extract of the herb Boswellia serrata showed significant reductions in symptoms of osteoarthritis. Seventy patients completed this 90 day, double blind, randomized, placebo controlled study.
Delicious Living ~ 1-01-2008
Herbal supplements can also reduce pain and help joint tissues heal. Boswellia (Boswellia serrata) and scullcap (Scutellaria lateriflora), for instance, are known to interfere with enzymes that contribute to inflammation. “These two work well together to inhibit the main inflammatory pain enzymes, COX-2 (cycloxygenase-2) and 5LO (5-lipoxygenase),” Talbott says. Move more, stress less.
A swollen big toe and a hobbled gait—finally, excruciating pain sends your customer to fill a prescription for allopurinol, the standard drug for treating gout. Are there natural remedies you can recommend to ease his suffering in addition to or instead of the pharmaceutical? YES! The enzyme xanthine oxidase catalyzes the last step in the conversion of purines to uric acid. Allopurinol, the medication prescribed for gout prevention, is a xanthine oxidase inhibitor. In vitro, xanthine oxidase is inhibited by the flavonoids luteolin and apigenin nearly as well as it is by allopurinol. [5] The flavonoids chrysin, baicalein, isorhamnetin, and several caffeic acid esters are also effective. [6]
Boswellia Abstracts
Vitro, Preclinical, Pharmacokinetic and Clinical Data
Clin Pharmacokinet. 2011 (Jun 1); 50 (6): 349–369
Non-steroidal anti-inflammatory drug (NSAID) intake is associated with high prevalence of gastrointestinal or cardiovascular adverse effects. All efforts to develop NSAIDs that spare the gastrointestinal tract and the cardiovasculature are still far from achieving a breakthrough. In the last two decades, preparations of the gum resin of Boswellia serrata (a traditional ayurvedic medicine) and of other Boswellia species have experienced increasing popularity in Western countries.
serrata Extracts and Boswellic Acids
Phytomedicine. 2010 (Sep); 17 (11): 862–867
From the pharmacological properties of BEs and BAs it is not surprising that positive effects of BEs in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.
Alternative Medicine Review 2008 (Jun); 13 (2): 165–167 ~ FULL TEXT
In vitro testing reveals boswellic acids, isolated from the gum resin of Boswellia, in a dose-dependent manner block the synthesis of proinflammatory 5-lipoxygenase products, including 5-hydroxyeicosatetraenoic acid (5-HETE) and leukotriene B4 (LTB4), [6] which cause bronchoconstriction, chemotaxis, and increased vascular permeability. [7]
Complementary Treatment of Asthma
Alternative Medicine Review 2001 (Feb); 6 (1): 20–47 ~ FULL TEXT
Antioxidant nutrients, especially vitamins C and E, selenium, and zinc appear to be necessary in asthma treatment. Vitamins B6 and B12 also may be helpful. Omega-3 fatty acids from fish, the flavonoid quercetin, and botanicals Tylophora asthmatica, Boswellia serrata and Petasites hybridus address the inflammatory component. Physical modalities, including yoga, massage, biofeedback, acupuncture, and chiropractic can also be of help.
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