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Commission E Monograph: Garlic
Name of Drug: Allii sativi bulbus, garlic clove.
Composition of Drug: Garlic bulbs, consisting of fresh or carefully dried bulbs that consist of the main bulb with several secondary bulbs (cloves) of Allium sativum L. [Fam. Alliaceae], as well as its preparations in effective dosage. Garlic contains alliin and its degradation products, and sulfur-containing essential oils.
Uses: Supportive to dietary measures at elevated levels of lipids in blood. Preventive measures for age-dependent vascular changes.
Contraindications: None known.
Side Effects: In rare instances there may be gastrointestinal symptoms, changes to the flora of the intestine, or allergic reactions. Note: The odor of garlic may pervade the breath and skin.
Interactions with Other Drugs: None known.
Dosage: Unless otherwise prescribed: average daily dosage 4 g fresh garlic [one medium clove]; equivalent preparations.
Mode of Administration: The minced bulb and preparations thereof for internal use.
Actions: Antibacterial, anti-mycotic, lipid-lowering, inhibition of platelet aggregation, prolongation of bleeding and clotting time, enhancement of fibrinolytic activity.
Reprinted with permission from The Complete German Commission E Monographs—Therapeutic Guide to Herbal Medicines, a 700-page guide featuring 380 monographs. The guide was published by the American Botanical Council, Austin, Texas, 1998
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