| PMC full text: | Published online 2007 Oct 24. doi: 10.1186/1475-2891-6-30
|
Table 5
Risk of suboptimal or elevated serum biomarker concentrations and elevated blood pressure by supplement user group.
| Outcome | Cases: n/(%) | OR* | 95% CI* |
| Homocysteine (>9 μmol/L) | |||
| Multiple Supp users | 30/(10.9) | 0.11 | 0.06–0.19 |
| Single Supp users | 69/(37.0) | 0.53 | 0.34–0.83 |
| No Supp users | 282/(45.3) | 1.00 | |
|
C-reactive protein (>0.3 mg/dL) | |||
| Multiple Supp users | 0/(0.00) | † | † |
| Single Supp users | 51/(30.6) | 0.66 | 0.40–1.09 |
| No Supp users | 230/(41.3) | 1.00 | |
|
Total cholesterol (>200 mg/dL) | |||
| Multiple Supp users | 145/(52.5) | 0.78 | 0.56–1.09 |
| Single Supp users | 89/(57.8) | 1.08 | 0.72–1.62 |
| No Supp users | 291/(54.3) | 1.00 | |
|
HDL-cholesterol (<40 mg/dL males, <50 mg/dL females) | |||
| Multiple Supp users | 44/(15.8) | 0.50 | 0.33–0.75 |
| Single Supp users | 40/(24.5) | 0.58 | 0.41–0.83 |
| No Supp users | 203/(38.0) | 1.00 | |
|
Ratio total cholesterol to HDL-cholesterol (<5) | |||
| Multiple Supp users | 35/(12.7) | 0.49 | 0.32–0.74 |
| Single Supp users | 48/(35.3) | 1.05 | 0.64–1.73 |
| No Supp users | 189/(36.5) | 1.00 | |
|
Triglycerides (≥150 mg/dL) | |||
| Multiple Supp users | 52/(18.8) | 0.44 | 0.27–0.71 |
| Single Supp users | 31/(41.5) | 0.99 | 0.50–1.94 |
| No Supp users | 157/(42.8) | 1.00 | |
|
LDL-cholesterol (>130 mg/dL) | |||
| Multiple Supp users | 109/(39.5) | 0.96 | 0.56–1.65 |
| Single Supp users | 32/(47.6) | 1.19 | 0.70–2.03 |
| No Supp users | 101/(42.7) | 1.00 | |
|
Blood Pressure (DBP>80 mmHg or SBP>120 mmHg) | |||
| Multiple Supp users | 154/(55.6) | 0.61 | 0.41–0.92 |
| Single Supp users | 117/(71.2) | 1.34 | 0.88–2.03 |
| No Supp users | 353/(64.6) | 1.00 |
* Logistic regression methods were used to estimate odds ratios (OR) with 95% confidence intervals (CI), adjusted as in footnote to Table 4. The referent group for risk estimation was the No Supp group.
†OR and 95% CI not estimable because zero events in the user group. Number and percent shown instead.
HDL = high-density lipoprotein, LDL = low-density lipoprotein, DBP = diastolic blood pressure, SBP = systolic blood pressure.