An overview of systematic reviews of complementary and alternative therapies for infantile colic

doi:10.1186/s13643-019-1191-5

Table 2

Results of AMSTAR-2

Author (date) CAM	1. Were PICO components listed?	2. Protocol reported? Any deviations justified?	3. Study design justified?	4. Comprehensive literature search?	5. Was study selection performed in duplicate?	6. Was data extraction performed in duplicate?	7. List of excluded studies? Were these justified?	8. Characteristics of studies provided in detail?	9. Risk of bias assessed?	10. Sources of funding of included studies?	11. Methods used to combine the findings of studies appropriate? Test on heterogeneity?	12. If meta-analysis performed was RoB accounted for?	13. Was RoB discussed in individual studies?	14. Was there discussion of any heterogeneity observed in the results?	15. If a quantitative synthesis, was publication bias investigated and discussed in relation to the results?	16. Reviewers’conflict of interests stated?	Confidence in the review
Multiple CAM therapies
Perry [22]	Yes	PY	No	PY	PY	Yes	No	Yes	Yes	No	No MA	No MA	Yes	No	No MA	Yes	Low
Bruyas-Bertholon [23]	No	No	No	No	No	No	No	PY	PY	No	No MA	No MA	No	No	No MA	No	CL
Harb [24]	Yes	No	No	No	Yes	Yes	No	PY	Yes	No	Yes	Yes	Yes	No	Yes	Yes	CL
Gutierrez-Castrellon [25]	Yes	No	No	No	No	No	No	No	No	No	No	No	Yes	No	Yes	No	CL
Manipulation therapies
Dobson [26]	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	No^a	Yes	Yes	High
Gleberzon [27]	No	No	No	PY	No	Yes	No	PY	No	No	No MA	No MA	Yes	No	No MA	No	CL
Carnes [28]	No	PY	No	PY	Yes	Yes	No	PY	Yes	No	No	No	No	No	No	No	CL
Acupuncture
Skejeie [29]	Yes	PY	No	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes	Yes	Yes	No	No^d	Low
Herbal medicines
Anheyer [30]	No	No	No	No	No	Yes	No	Yes	Yes	No	No MA	No MA	No	No	No MA	Yes	CL
Probiotics
Sung [31]	Yes	No	No	No	Yes	Yes	Yes	PY	Yes	No	Yes	No	Yes	No	No	Yes	CL
Anabrees [32]	Yes	PY	No	PY	No	Yes	No	Yes	Yes	No	Yes	No	Yes	Yes	No	Yes	Low
Urbanska [33]	Yes	No	No	PY	No	No	No	PY	Yes	Yes	No	No	No	No	No	No	CL
Xu [34]	No	No	No	PY	Yes	Yes	No	Yes	Yes	No	Yes	No	No	No	No	Yes	CL
Schreck Bird [35]	Yes	No	No	No	Yes	No	No	Yes	Yes	No	No	No	No	No	No	No	CL
Dryl [36]	Yes	No	No	No	No	No	No	PY	Yes	No	No	No	No	No	No	No	CL
Sung [37]	Yes	PY	No	PY^b	No	No	No	No	Yes	No	Yes	Yes	Yes	Yes	Yes	No^c	Low

CL critically low, PY partial yes, MA meta-analysis, PICO participants, intervention, comparator, outcomes, RoB risk of bias

Grey columns represent the critical domains (see Additional file 1)

^aToo few studies to perform a test of heterogeneity

^bNot fully searched and search conducted Dec 2014

^cConflict of interest occurred but no indication of how it was dealt with

^dAll included studies were by the author team but did not indicate how this was dealt with