Plasmacytoma of the Cervical Spine: A Case Study

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Published online 2017 Mar 2. doi: 10.1016/j.jcm.2015.10.001

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Table 1

Summary of Nonmechanical Causes of Neck and Back Pain

Condition	Average Age at Diagnosis	Clinical Presentation	Location in Body	Presentation in Vertebral Body
Metastasis	50-70¹	Night pain, weight loss, cachexia	Any	Lytic or blastic destruction


Multiple myeloma	60-70¹	Widespread bone pain, fatigue	Axial skeleton	Punched-out lytic lesions


Plasmacytoma	50¹	Focal bone pain, possible neurologic compromise	Axial skeleton	Bubbly, expansile lytic destruction


Lymphoma	10-60¹	Lymphadenopathy, fever, night sweats	Lymph nodes, spleen	Lytic or blastic destruction


Eosinophilic granuloma	10-20¹	Local pain, tenderness, and swelling	Axial skeleton, especially the skull	Lytic destruction leading to flattening (vertebra plana)


Spondylodiscitis/infection	5-20¹	Fever, swelling, palpable mass	Intervertebral discs	Endplate destruction


Osteoblastoma	10-30¹	Focal bone pain sometimes reduced by aspirin	Posterior elements of spine	Bubbly, lytic destruction