Phytotherapy Influences Atrophic Vaginal Epithelium

Phytotherapy Influences Atrophic Vaginal Epithelium

This section is compiled by Frank M. Painter, D.C.
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FROM:   Therapeuticon 1987;   1:   23-31

Stoll W.

The hazards of a prolonged estrogen therapy of the menopausal syndrome are controversially discussed which reinforces a growing interest among the patients in alternatives like phytotherapy.

To test the effectiveness of a plant derived medicament (Remifemin®, a Cimicifuga racemosa aka black cohosh preparation), a double blind study was conducted with 80 women between 46 and 58 years, comparing a low dose estrogen, the phytopharmacon and a placebo group. 30 of the volunteers received 0.625 mg of conjugated estrogens per day, another 30 volunteers were given 8 mg of a standardized cimicifuga extract and 20 patients got placebo.

The parameters under investigation were:

1) the menopausal index according to Kupperman, measuring mainly neurovegetative symptoms.

2) the Hamilton anxiety scale for psychological complaints and

3) the proliferation status of vaginal epithelium as an objective parameter.

1) and 2) were investigated every four weeks, 3) at the beginning and the end of the study after 12 weeks.

After three months of therapy with the phytotherapeuticon, all three parameters had significantly improved. The applicated estrogen does proved to be too low, and yielded no effect compared to placebo.

The usefulness of the phytopharmacon Remifemin® as an alternative to estrogen could be substantiated.


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