FROM: Anaesthesist 1975 (Aug; 24 (8): 329–342
In the present experimental study, 36 rabbits were subjected to
fracture of the of the fibula and were treated in 3 groups viz.,
Control group, Zinc sulphate supplemented group and Zinc sulphate
vit. C. + Methandienone supplemented group. Each group consisted
of 12 rabbits. After roentgenological, macroscopic and
histological examination of healing of fractures of weekly
intervals, it was concluded that the Zinc supplementation to an
appreciable extent enhanced the process of bone healing which
could be further hastened by addition of Vitamin C and Dianabol.
No significant toxic or side effect of zinc supplementation was
observed in any of the rabbits. A clinical trial of the same
drugs was also conducted in patients with fractures of the shaft
of the femur.